Journal of the Korean Chemical Society (대한화학회지)

Korean Chemical Society (대한화학회)
권호 표지

Synthesis of Nucleophilic Adducts of thiols (VIII). Addition of Thioglycolic acid, Benzenethiol and Benzylmercaptan to ${\beta}$-Acetyl-${\beta}$-benzoylstyrene Derivatives

Thiol의 친핵성 첨가물의 합성 (제VIII보) ${\beta}$-Acetyl-${\beta}$-benzoylstyrene 유도체에 대한 thioglycolic acid, benzenethiol 및 benzylmercaptan 첨가 생성물의 합성

  • Tae-Sung Huh (Department of Chemistry, Song Sim College for Women) ;
  • In-Sook Baek (Department of Chemistry, Song Sim College for Women) ;
  • Kih-Rim Seo (Department of Chemistry, Song Sim College for Women) ;
  • Tae-Rim Kim (Department of Chemistry, Korea University)
  • 허태성 (성심여자대학 화학과) ;
  • 백인숙 (성심여자대학 화학과) ;
  • 서기림 (성심여자대학 화학과) ;
  • 김태린 (고려대학교 이과대학 화학과)
  • Published : 1987.08.20
Download PDF
⟨ Previous Next ⟩

Abstract

The addition reactions of thioglycolic acid, benzenethiol and benzylmercaptan to ${\beta}-acetyl-{\beta}-benzoylstyrene$ were investigated. ${\beta}-Acetyl-{\beta}-benzoylstyrene$ derivatives easily underwent addition reactions with thioglycolic acid, benzenethiol, and benzylmercaptan to form five(2-acetyl-2-benzoyl-1-phenylethyl) thioglycolic acid derivatives (IIa-IIe), five (2-acetyl-2-benzoyl-1-phenylethyl)benzenethiol (IIIa-IIIe) derivatives and five (2-acetyl-2-benzoyl-1-phenylethyl)benzylmercaptan derivatives (IVa-IVe), respectively.

${\beta}-Acetyl-{\beta}-benzoylstyrene$ 유도체에 대한 thioglycolic acid, benzenethiol 및 benzylmercaptan의 첨가반응에 관하여 연구하였다. ${\beta}-acetyl-{\beta}-benzoylstyrene$ 유도체는 쉽게 thioglycolic acid, benzenethiol, benzylmercaptan과 반응하여 다섯가지 (2-acetyl-2-benzoyl-1-phenylethyl) thioglycolic acid 유도체 (IIa-IIe), 다섯가지의 (2-acetyl-2-benzoyl-1-phenylethyl)benzenethiol 유도체 (IIIa-IIIe) 및 다섯가지의 (2-acetyl-2-benzoylphenylethyl)benzylmercaptan 유도체 (IVa-IVe)를 합성한다.

Keywords

References

  1. The chemistry of alkenes S. patac;Z. Rappoport;S. patac(ed.)
  2. The chemistry of the hydroxyl group C. A. Fzfe;S. patac(ed.)
  3. J. Am. Chem. Soc. v.108 C. F. Bernasconi;R. A. Renfrow;P. R. Tia
  4. Nature v.233 R. A. Alarcon;J. Meinhofer
  5. Biochem. Pharmacol. v.22 H. Zoller
  6. Biochem. Biophys. Acta. v.228 R. W. Kims;D. R. Morris
  7. Europ. J. Cancer v.11 P. J. Conroy;J. T. Nodes;T. F. Slator;G. W. White
  8. J. Korean Chem. Soc. v.25 no.6 T. R. Kim.;T. S. Huh;I. S. Han
  9. Bull. Korean Chem. Soc. v.5 T. S. Huh;H. S. Han;I. S. Han;T. R. Kim
  10. Bull. Korean Chem. Soc. v.7 T. S. Huh;H. J. Lee;I. S. Han;T. R. Kim