A Dtudy on the Effect of Polyamines of Korean Red Ginseng on the Growth of Cultured Chichen Embryonic Muscle Cells

홍삼 Polyamine 계 성분이 배양한 계배의 근육세포 성장에 미치는 영향

Polyamines of Korean red ginseng were extracted with 5% trichloroacetic acid and purified by ion exchange chromatography using Dowex-50Wx8 resin. Four spots having R$_f$ values of 0.19, 0.28, 0.35, and 0.45 were detected. It was observed under microscopy that those polyamines stimulated the growth and differentiation of chicken embryonic muscle cell. The development of muscle cells from the stage of myoblast to that of myotube was found to be enhanced by those polyamines. It was also observed that those polyamines most likely lengthened, the life-span of the cultured chicken embryonic skeletal muscle cells.