Journal of Pharmaceutical Investigation
- Volume 17 Issue 2
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- Pages.95-98
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- 1987
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Drug Interaction of Probenecid and Lithium Carbonate
프로베네시드와 탄산리튬의 약물상호작용
- Lee, Jin-Hwan (College of Pharmacy, Chosun University) ;
- Lee, Chong-Ki (College of Pharmacy, Chosun University)
- Published : 1987.06.20
Abstract
The drug interaction between probenecid and lithium carbonate was studied pharmacokinetically in rabbits. The blood level and the area under the concentration curve (AUC) of lithium carbonate administered orally were elevated by coadministration of probenecid. Probenecid inhibited the urinary excretion of lithium carbonate in rabbits. Biological half-life and
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