Journal of Pharmaceutical Investigation

  • 제17권1호
  • /
  • Pages.22-30
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  • 1987
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  • 2093-5552(pISSN)
  • /
  • 2093-6214(eISSN)
한국약제학회 (The Korean Society of Pharmaceutical Sciences and Technology)
권호 표지

생약 복합제제의 품질평가에 관한 연구(제 2 보) -생진산(生賑散)의 품질평가 방법에 관하여-

Studies on Quality Evaluation of Crude Drug Preparation(II) -Analysis of Saengmaek-san by Thin Layer Chromatography and High Performance Liquid Chromatography-

  • Hong, N.D. (Medical Center, Kyung-Hee University) ;
  • Kim, J.W. (Medical Center, Kyung-Hee University) ;
  • Won, D.W. (National Institute of Health) ;
  • Kong, Y.C. (Chinese University of Hong Kong) ;
  • Kim, N.J. (Medical Center, Kyung-Hee University) ;
  • Joo, S.M. (Medical Center, Kyung-Hee University)
  • 발행 : 1987.03.20
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초록

Evaluation method of crude drug preparations was studied in Saengmaek-san. Zig-zag TLC scanning profiles and high performance liquid chromatograms were obtained from Saengmaek-san and its each crude drug. A method using TLC densitometry and high performance liquid chromatography was established for the precise determination of ginsenoside $Rb_1$ in Saengmaek-san containing Ginseng Radix. Consequently, ginsenosicle $Rb_1$ content was 0.45-0.48 mg per g of Saengmaek-san. This method was found to be useful for the quality evaluation of oriental medicinal preparations.

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