생약학회지 (Korean Journal of Pharmacognosy)
- 제18권1호
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- Pages.5-13
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- 1987
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
들깨유 섭취가 흰쥐의 출혈시간, 트롬복산 생성 및 혈소판의 지방산 조성에 미치는 영향
Effects of Perilla Oil Intake on Bleeding Time, Thromboxane Formation and Platelet Fatty Acid in Rats
- Han, Yong-Nam (Natural Products Research Institute, Seoul National University) ;
- Yoon, Hae-Won (Department of Foods and Nutrition, Ewha Womans University) ;
- Kim, Sook-Hee (Department of Foods and Nutrition, Ewha Womans University) ;
- Han, Byung-Hoon (Natural Products Research Institute, Seoul National University)
- 발행 : 1987.03.30
초록
Male rats were fed diets containing perilla oil, sardine oil or corn oil for 15 weeks in order to investigate their antithrombotic effects. Rats given perilla oil and sardine oil diets showed significantly longer bleeding time, and lower level of malondialdehyde generation during thrombin-induced aggregation of platelets than rats given corn oil. With regard to the composition of platelet fatty acid, the ratio of eicosapentaenoic acid(EPA)