The Journal of the Korean Society for Microbiology (대한미생물학회지)

The Korea Society for Microbiology (대한미생물학회)
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A Study on the Mating Types and Serotypes of Clinical Isolates of Cryptococcus neoformans and Production of Serodiagnostic Antigen and Antiserum for Cryptococcosis

우리나라 환자로부터 분리된 Cryptococcus neoformans의 균학적 특성과 혈청학적 진단용 항원 및 항체생산에 관한 연구

  • Kim, Sang-Jae (Korean Institute of Tuberculosis, Korean National Tuberculosis Association) ;
  • Kim, Sin-Ok (Korean Institute of Tuberculosis, Korean National Tuberculosis Association) ;
  • Lee, Seung-Ho (Korean Institute of Tuberculosis, Korean National Tuberculosis Association) ;
  • Chong, Yon-Sop (Department of Clinical Pathology, Yonsei University) ;
  • Suk, Jong-Sung (Department of Clinical Pathology Seoul National University Hospital)
  • 김상재 (대한결핵협회 결핵연구원) ;
  • 김신옥 (대한결핵협회 결핵연구원) ;
  • 이승호 (대한결핵협회 결핵연구원) ;
  • 정윤섭 (연세대학교 의과대학 임상병리과) ;
  • 석종성 (서울대학교 임상병리과)
  • Published : 1986.03.31
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Abstract

The mating types and serotypes of 10 clinical isolates of Cryptococcus neoformans have been investigated. Seven isolates were serotype A and three were serotype D and thus they fell in C. neoformans var. neoformans. Mating types of six isolates were found $\alpha$ and two were $\alpha$ but another two isolates were untypable. Enzyme linked immuno-sorbent assay(ELISA) using rabbit hyper-immune serum to cryptococcal polysaccharides was well adapted to the analysis of capsular polysaccharides in sera of the patients with cryptococcal meningitis.

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