The Journal of the Korean Society for Microbiology (대한미생물학회지)
- Volume 21 Issue 2
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- Pages.181-189
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- 1986
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- 0253-3162(pISSN)
Diagnosis of Leptospirosis by Enzyme-liked Immunosorbent Assay
효소면역측정법에 의한 렙토스피라증 진단의 검토
- Park, Kyung-Hee (Department of Microbiology, Cancer Research Institute, College of Medicine, Seoul National University) ;
- Chang, Woo-Hyun (Department of Microbiology, Cancer Research Institute, College of Medicine, Seoul National University) ;
- Lee, Jung-Sang (Department of Internal Medicine, Carcer Research Institue, College of Medicine, Seoul National University) ;
- Choi, Kang-Won (Department of Internal Medicine, Carcer Research Institue, College of Medicine, Seoul National University) ;
- Park, Kyung-Suck (Division of Microbiology, National Institute of Health) ;
- Oh, Hee-Bok (Division of Microbiology, National Institute of Health)
- 박경희 (서울대학교 의과대학 미생물학교실, 암연구소) ;
- 장우현 (서울대학교 의과대학 미생물학교실, 암연구소) ;
- 이정상 (서울대학교 의과대학 내과학교실, 암연구소) ;
- 최강원 (서울대학교 의과대학 내과학교실, 암연구소) ;
- 박경석 (국립보건원 미생물부) ;
- 오희복 (국립보건원 미생물부)
- Published : 1986.06.30
Abstract
To apply ELISA to serodiagnosis of leptospirosis with killed whole cells from Leptospira interrogans serovars mwogolo (Mwogolo), copenhageni (M-20), WH-20, autumnalis (Akiyami A), cynopteri (3522 C), australis (Bacillico) and Leptospira biflexa serovar patoc (patoc 1), sensitivity and specificity was evaluated. The reactivity of IgM and IgG antibody in the sera from patients with leptospirosis, hemorrhagic fever with renal syndrome and other febrile disease and normal healthy control to the killed whole cells was analysed. The results were summarized as follows. 1. The reactivity (absorbance at 492mn) of IgM and IgG to L. mwogolo antigen in the sera of pattients with leptospirosis were