The Journal of the Korean Society for Microbiology (대한미생물학회지)
- Volume 21 Issue 3
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- Pages.375-380
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- 1986
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- 0253-3162(pISSN)
Combined action of Aminoglycoside and Cephalosporin Against Pseudomonas aeruginosa
녹농균에 대한 Aminoglycoside계와 Cephalosporin계의 병합작용
- Oh, Jong-Suk (Department of Microbiology, Chonnam National University Medical School) ;
- Ahn, Tai-Hew (Department of Microbiology, Chonnam National University Medical School)
- Published : 1986.09.30
Abstract
Thirty-one strains of Pseudomonas aeruginosa were submitted to the synergistic activity test of amikacin(AK) and gentamicin(GM) combined with moxalactam(MX), ceftizoxime(CTZ) or cefoperazone(CFZ). The minimal inhibitory concentrations(MICs) of each drug and drugs combined in various ratios were measured by checkerboard dilution method. The synergism was determined through analysing the MIC distribution curve on isobologram and calculating the fractional inhibitory concentration index(FICI). MICs of GM, AK, MX, CFZ and CTZ against the 31 tested strains were distributed from