Quantitation of Intracardiac Right-to-Left Shunt by Radionuclide Angiocardiography

방사성동위원소 심혈관촬영술을 이용한 우-좌단락의 정량화에 관한 연구

  • Bom, Hee-Seung (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lim, Sang-Moo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Oh, Yeon-Sang ;
  • Kim, Byung-Tae ;
  • Chung, June-Key (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Chul (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Young-Woo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Yun, Yong-Soo (Department of Pediatrics, College of Medicine, Seoul National University) ;
  • Hong, Chang-Yee (Department of Pediatrics, College of Medicine, Seoul National University)
  • 범희승 (서울대학교 의과대학 내과학교실) ;
  • 임상무 (서울대학교 의과대학 내과학교실) ;
  • 오연상 (중앙대학교 의과대학 내과학교실) ;
  • 김병태 (한림대학교 의과대학 내과학교실) ;
  • 정준기 (서울대학교 의과대학 내과학교실) ;
  • 이명철 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 이영우 (서울대학교 의과대학 내과학교실) ;
  • 윤용수 (서울대학교 의과대학 소아과학교실) ;
  • 홍창의 (서울대학교 의과대학 소아과학교실)
  • Published : 1986.12.31

Abstract

A noninvasive procedure for diagnosis and quantitation of right-to-left intracardiac shunts will enhance the management of patients with cyanotic congenital heart disease. This study describes an application of radionuclide (RN) angiocardiography for quantitation of right-to-left shunt amount. Gamma variate model was fitted to radionuclide data recorded over the carotid artery. Data analysis was performed retrospectively in 35 patients who underwent cardiac catheterization within a week from the day of RN angiocardiography. Thirty one of the patient had right-to-left shunts and 4 of them had left-to-right shunts. Both the radionuclide and Fick measurements correlated well (r=0.93, 0.93, 0.89, p<0.01 in each measurements). Therefore, RN angiocardiography data may be used for accurate calculation of right-to-left shunts in cyanotic congenital heart disease patients.

Keywords