Journal of the Korean Chemical Society (대한화학회지)

Korean Chemical Society (대한화학회)
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Transition Metal Catalyzed the Double Hydrohydroxymethylation of Carbonyl Compounds by a Carbon Monoxide-Water System

전이금속촉매-일산화탄소-물계에 의한 카르보닐화합물의 이중 히드로히드록시메틸화 반응

  • Sang Chul Shim (Department of Industrial Chemistry, Kyungpook National University) ;
  • Kyung Eun Min (Department of Industrial Chemistry, Kyungpook National University) ;
  • Keun Tae Huh (Department of Industrial Chemistry, Kyungpook National University)
  • 심상철 (경북대학교 공과대학 공업화학과) ;
  • 민경은 (경북대학교 공과대학 공업화학과) ;
  • 허근태 (경북대학교 공과대학 공업화학과)
  • Published : 1986.02.20
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Abstract

Dialdehydes such as adipaldehyde, glutaraldehyde, and succinaldehyde were readily reduced to give their corresponding 1,6-hexanediol, 1,5-pentanediol, and 1,4-butanediol in good yields in the presence of catalytic amount of hexarhodium hexadecacarbonyl or iron pentacarbonyl in water and methoxyethanol or ethanol at 180$^{\circ}C$ for 4 hr under carbon monoxide atmosphere. Under the same reaction conditions, diketones such as 2,5-hexanedione, 2,4-pentanedione, and 2,3-butanedione afforded their corresponding 2,5-hexanediol, 2,4-pentanediol and 2,3-butanediol in moderate yields. For double hydrohydroxymethylation of dialdehydes or diketones, rhodium or iron carbonyl complexes are more effective than others. Particularly, benzoquinone gave hydroquinone quantitatively.

아디파알데히드, 구르타르알데히드 및 숙신알데히드와 같은 디알데히드는 물-에톡시에탄올 및 에탄올내에 촉매량의 육로듐 십육카르보닐 또는 오카르보닐철의 존재하, 70기압, 일산화탄소, 180$^{\circ}C$, 4시간동안 반응시켜 쉽게 환원되어 대응하는 1,6-헥산디올 및 1,5-펜탄디올 및 1,4-부탄디올이 좋은 수득율로 얻어졌다. 같은 조건하에서 2,5-헥산디온, 2,4-펜탄디온도 대응하는 디올이 보통 수득율로 얻어졌다. 디알데히드의 이중 히드로히드록시메틸화 반응에 대해서는 금속카르보닐 촉매가 다른 촉매보다 더욱 활성적이다. 특히 벤조퀴논은 정량적으로 히드로퀴논을 주었다.

Keywords

References

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