Bulletin of the Korean Chemical Society

  • 제7권6호
  • /
  • Pages.425-428
  • /
  • 1986
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Reaction of Lithium 2-Pyridyloxyalkylcuprates Having Improved Thermal Stability with Acid Chlorides and $\alpha,\beta$-Unsaturated Ketones

  • Lee, Phil-Ho (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
  • Shim, Sang-Chul (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
  • Kim, Sung-Gak (Department of Chemistry, Korea Advanced Institute of Science and Technology)
  • 발행 : 1986.12.20
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초록

A new heterocuprate containing 2-pyridyloxy ligand, lithium 2-pyridyloxy-n-butylcuprate, has shown improved thermal stability and it reacts with acid chlorides to afford the corresponding ketones in high yields. Similarly, it can be effectively utilized in conjugate addition reactions of $\alpha,\beta$-unsaturated ketones. Of synthetic significance is that the complete utilization of n-butyl group in lithium 2-pyridyloxy-n-butylcuprate has been observed.

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참고문헌

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피인용 문헌

  1. Indium-Mediated &bgr;-Allylation, &bgr;-Propargylation, and &bgr;-Allenylation onto &agr;,&bgr;-Unsaturated Ketones: Reactions of in-Situ-Generated 3-tert-Butyldimethylsilyloxyalk-2-enylsulfonium Sal vol.125, pp.32, 2003, https://doi.org/10.1021/ja035988m
  2. Regioselective Addition Reactions of the Organoindium Reagents onto α,β-Unsaturated Ketones vol.25, pp.11, 1986, https://doi.org/10.5012/bkcs.2004.25.11.1687
  3. Indium and Gallium-Mediated Addition Reactions vol.28, pp.1, 2007, https://doi.org/10.5012/bkcs.2007.28.1.017