Journal of Food Hygiene and Safety (한국식품위생안전성학회지)
- Volume 1 Issue 1
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- Pages.13-21
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- 1986
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- 1229-1153(pISSN)
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- 2465-9223(eISSN)
Mutagenic and Clastogenic Activities of the Browning Reaction Model Systems
- Ryu, Beung-Ho (Department of Food Science and Technology) ;
- Kim, Dong-Seuk (Department of Food Science and Technology) ;
- Kim, Dong-Su (Department of Food Science and Technology) ;
- Lee, Chong-Choil (Department of pharmacy)
- Published : 1986.11.01
Abstract
Two short-term bioassays were employed to asses the mutagenic and clastogenic activities in browning reaction of pentose-creatine, pentose-glycine and pentose-creatine-glycine browning reaction model system. Methylene chloride extract of rhamnose-creatine-glycine browning reaction exhibited the strongest mutagenicity toward Salmonella typhimurium TA98 with S-9. Methylene chloride extract of pentose-creatine and pentose-glycine browning reaction solutions was also tested for mutagenicity, with positive responses. Methylene chloride extract of pentose-creatine-glycine browning reaction solutions induced significant increase in chromosome aberrations in the treated Chinese hamster ovary(CHO) cells. Each of pentose-creatine and pentose-glycine browning reaction solutions induced a relatively low frequency of chromosome aberrations in the treated cells.
Keywords
- Mutagenic and Clastogenic Activities;
- Browning reaction;
- Salmonella typhimurium TA98;
- Chromosome aberration