약학회지 (YAKHAK HOEJI)
- 제30권5호
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- Pages.238-244
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- 1986
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
1-$\beta$ -D-Arabinofuranosylcytosine-5'-methylthioacetate의 합성 및 이의 DNA 합성애 대한 억제작용 평가
Synthesis of 1-$\beta$ -D-Arabinofuranosylcytosine-5'-methylthioacetate and Evaluation of Its Inhibitory Effect on DNA Synthesis
초록
As one of the starting materials, methylthioacetyl chloride(7) was synthesized in fair yield from mercaptoacetic acid via methyl methylthioacetate(5) prepared by alkylation employing N, N'-dicyclohexyl-O-methylisourea(4). Then 1-
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