Biopharmaceutical Studies on the Alkanol Esters of Naproxen(I) -Studies of 3 Kinds Alkanol Esters of Naproxen-

나프록센의 Alkanol 에스테르류에 관한 생물약제학적 연구 I -3종의 Alkanol 에스테르의 합성-

  • Published : 1986.06.01

Abstract

Three new alkanol esters of d-2-(6-methoxy-2-naphthyl)propionic acid, NAPROXEN were synthesized by esterification of sodium naproxen with chloralcohols, such as 2-chloroethanol, 3-chloro-1, 2-propanediol and $\beta$-chloroethoxyethanol in dimethylformamide. These new esters were obtained with comparably high yield and identified by elemental analysis, UV, IR and NMR techniques.

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