The Glycosides of Araliaceaus Drugs and their Biological Activities

  • Hahn, Dug-Ryong (College of Pharmacy, Chung-Ang University) ;
  • Kasai, Ryoji (Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine) ;
  • Kim, Jeung-Hee (College of Pharmacy, Won Kwang University) ;
  • Taniyasu, Shigenori (Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine) ;
  • Tanaka, Osamu (Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine) ;
  • Kim, Chang-Johng (College of Pharmacy, Chung-Ang University) ;
  • Park, Myong-Ja (College of Pharmacy, Chung-Ang University)
  • 발행 : 1986.03.30

초록

Among the Araliaceae plants indigenous to Korea, those whose medicinal usage are comparatively high have been selected in this serial studies. Chiisanoside and acanthoside D were isolated and identified from the Acanthopanax chinensis leaves and root bark. Chiisanoside and acanthoside D have been found to have the lowering S-GPT, S-GOT value and BSP-retention rate and survival rate, anti-histaminic effect in the toxic state through the bio-pharmacological experiments. ${\alpha}-hederin$, hederagenin pentaglycoside were isolated both stem bark of Kalopanax pictum Nakai var. magnificum and Kalopanax pictum Nakai var. Max. respectively. Syringoside, acanthoside D were also isolated from the root bark of Acanthopanax koreanum. The biological activity of ginsenoside $Rb_1$, $Rg_1$, Re were examined. Ginsenoside $Rb_1$, $Rg_1$, Re promotes the antileaking effect in X-ray (Co 60) irradiated toxic state.

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