대한미생물학회지 (The Journal of the Korean Society for Microbiology)
- 제20권1호
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- Pages.79-89
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- 1985
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- 0253-3162(pISSN)
결핵균 및 기타 3종 Mycobacteria의 파쇄추출항원과 교차반응하는 폐결핵환자의 항체분석
Analysis of Antibodies Cross-reactive with Pressate Extract Antigen from Mycobacterium tuberculosis and Other 3 Species Mycobacteria in Sera of Patients with Pulmonary Tuberculosis
- 조명제 (서울대학교 의과대학 미생물학교실.암연구소) ;
- 황응수 (서울대학교 의과대학 미생물학교실.암연구소) ;
- 국윤호 (서울대학교 의과대학 미생물학교실.암연구소) ;
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김익상
(서울대학교 의과대학 미생물학교실.암연구소) ;
- 이승훈 (서울대학교 의과대학 미생물학교실.암연구소) ;
- 차창용 (서울대학교 의과대학 미생물학교실.암연구소) ;
-
심영수
(서울대학교 의과대학 미생물학교실.결핵연구소) ;
- 한용철 (서울대학교 의과대학 미생물학교실.결핵연구소) ;
- 배길한 (대한결핵협회 대한결핵연구원) ;
- 김상재 (대한결핵협회 대한결핵연구원)
- Cho, Myung-Je (Department of Microbiology, Cancer Research Institutes, Seoul National University) ;
- Hwang, Eung-Soo (Department of Microbiology, Cancer Research Institutes, Seoul National University) ;
- Kook, Yoon-Hoh (Department of Microbiology, Cancer Research Institutes, Seoul National University) ;
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Kim, Ik-Sang
(Department of Microbiology, Cancer Research Institutes, Seoul National University) ;
- Lee, Seoung-Hoon (Department of Microbiology, Cancer Research Institutes, Seoul National University) ;
- Cha, Chang-Yong (Department of Microbiology, Cancer Research Institutes, Seoul National University) ;
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Shim, Young-Soo
(Department of Microbiology, Tuberculosis Institutes, Seoul National University) ;
- Han, Yong-Chol (Department of Microbiology, Tuberculosis Institutes, Seoul National University) ;
- Bae, Gill-Han (Korean Institures of Tuberculosis, Korean National Tuberculosis Association) ;
- Kim, Sang-Jae (Korean Institures of Tuberculosis, Korean National Tuberculosis Association)
- 발행 : 1985.12.31
초록
It is important to discriminate between tuberculosis and tuberculosis-like disease by Mycobacteria other than tuberculosis in the serodiagnosis of tuberculosis. But because common antigens share among Mycobacteria, their antigenicities to human are similar. Therefore degree of cross-reactivity of antibody in the sera of patients with tuberculosis between M. tuberculosis and Mycobacteria other than tuberculosis should be checked to increase the specificity in the serodiagnosis of tuberculosis. The activity levels of IgG antibody in the sera of 106 patients confirmed as active pulmonary tuberculosis and 30 normal healthy control person to the pressate extract antigen (TE, BE, AE, and FE antigen) from M. tuberculosis, M. bovis, M. avium, and M. fortuitum were measured by enzyme-linked immunosorbent assay and the crossreactivity of IgG antibody with mycobacterial species was analysed. The results were as follows; 1. The activity level(O.D. at 492nm) of IgG to TE antigen in sera of patients with pulmonary tuberculosis was
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