Abstract
The adsorption of quinine, atropine and methylrozaniline chloride from aqueous phase by different kaolins was studied to innovated utilization of Korean kaolins as pharmaceutical agents. The adsorption isotherms were determined at $27{\pm}1^{\circ}C$ and the results were plotted according to the Langmuir equation. The Langmuir constants were calculated from adsorption isotherms of quinine and methylrozaniline chloride; a=1.46, 1.34 b=5.7, 9.3 and slope=0.175, 0.108, respectively. The kaolins gave the same type of curves with the two alkaloids and methylrozaniline chloride. The white colored premium grade kaolins were better adsorbent for the alkaloids and methylrozaniline chloride than the lower grade ones. The results indicate that the premium grade kaolins could be utilized as an ingredients in intestinal preparations. The condition of activation for the better adsorption was under the cases with the higher temperature and the lower pressure. The smaller particle size, the greater was adsorption power and the activated kaolins had superior adsorptive properties at higher pH value than at higher hydrogen-concentrations.