Archives of Pharmacal Research
- 제8권4호
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- Pages.229-236
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- 1985
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Studies on Triterpenoid Corticomimetics (V) - Oxidation of Presenegenin with Chromium Trioxide-Acetic Acid to Yield 11-Keto and 12-Keto Derivatives
- Han, Byung-Hoon (Natural Products Research Institute, Seoul National University) ;
- Han, Yong-Nam (Natural Products Research Institute, Seoul National University)
- 발행 : 1985.12.01
초록
Oxidation of presenegenin dimethyl ester triacetate with chromium trioxide in acetic acid yielded two compounds, 11-ketone (IV) and 12-ketone (IV) derivatives. The latter was a main product. On mild alkaline hydrolysis, IV afforded 11-keto-presenegenin dimethyl ester (V), mp 232-