Journal of Nutrition and Health
- 제18권3호
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- Pages.242-248
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- 1985
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- 2288-3886(pISSN)
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- 2288-3959(eISSN)
장기간의 Pyridoxine 부족이 흰쥐 뇌의 지방산 조성에 미치는 영향
Effect of Long-Term Pyridoxine Depletion on the Fatty Acid Composition of the Rat Brain
- Choi, Hay-Mie (Dept. of Food of Nutrition, Seoul National University) ;
- Lee, Hong-Mie (Dept. of Food of Nutrition, Seoul National University) ;
- Kim, Jung-Hee (Dept. of Food of Nutrition, Seoul National University)
- 발행 : 1985.09.30
초록
Weanling female Sprague Dawley rats were fed diets containing 22mg pyridoxine HCI/kg diet(control diet) and 1.2mg pyridoxine HCI/kg diet(deficient diet). One deficient group and one control group were fed their diets throughout the period of growth, gestation and lactation. After the pups were born and weaned, the deficient group was divided into two groups. Therefore, one(DC) switched to control diet and the other continued the same deficient diet until 10 week-old. Analysis of chemical composition of fatty acid in the total brain lipid was conducted in the pups of 5, 10, 15, 21, 35, 50 days of age. Arachidonic acid content was significantly decreased in the deficient group at 5 days compared to the control, but at almost all ages, there were no significant differences in fatty acid contens among all the groups. The fatty acid compositions of the brain phospholipids were determined on pups at 1, 14, 21, 35, 70 days of age. The content of
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