Synthesis and Anti-inflammatory Activity of Fenbufen-Acetaminophen Ester

Fenbufen-Acetaminophen Ester의 합성 및 항염 작용

Synthetic procedures to synthesize fenbufen-acetaminophen ester were searched by acid chloride method, DCC method and mixed acid anhydride method. The compound was synthesized by DCC method and mixed acid anhydride method but could not be synthesized by acid chloride method. Its anti-inflammatory activity was superior to acetaminophen and similar to fenbufen.