Identification of N-acetyl and hydroxylated N-acetyltranylcypromine from tranylcypromine-dosed rat urine

  • Published : 1984.06.01

Abstract

Mechanism of the monoamine oxidase inhibition by tranylcypromine was studied in relation to its metabolism to reactive apecies. A metabolic study performed to collect general biotransformation pathway in rats provided GC/MS evidence for the detection of two new metabolites, N-acetyl and hydroxylated N-acetyltranylacypromine.

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