Archives of Pharmacal Research
- 제7권1호
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- Pages.65-68
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- 1984
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Identification of N-acetyl and hydroxylated N-acetyltranylcypromine from tranylcypromine-dosed rat urine
- Kang, Gun-Il (College of Pharmac, Sookmyung Womens University) ;
- Chung, Soon-Young (College of Pharmac, Sookmyung Womens University)
- 발행 : 1984.06.01
초록
Mechanism of the monoamine oxidase inhibition by tranylcypromine was studied in relation to its metabolism to reactive apecies. A metabolic study performed to collect general biotransformation pathway in rats provided GC/MS evidence for the detection of two new metabolites, N-acetyl and hydroxylated N-acetyltranylacypromine.
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