Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)
- Volume 13 Issue 1
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- Pages.22-26
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- 1984
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- 1226-3311(pISSN)
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- 2288-5978(eISSN)
Effect of Mercuric Chloride on the Contents of Mineral Nutrients in the Liver and Kidney of Rats
흰쥐의 간장(肝臟) 및 신장(腎臟) 무기질(無機質)에 미치는 수은(水銀)의 영향(影響)
- Cho, Soo-Yeul (Dept. of Environmental Science, Graduate School of Environmental Studies, Yeungnam University) ;
- Park, Sun-Woo (Dept. of Environmental Science, Graduate School of Environmental Studies, Yeungnam University) ;
- Lee, Sang-Il (Dept. of Environmental Science, Graduate School of Environmental Studies, Yeungnam University)
- Published : 1984.03.31
Abstract
The effect of changes in body weight, some blood components and some inorganic ions in liver and kidney, were studied on male rats receiving ad libitum on 5, 40, and 200 ppm of mercuric chloride solution during so days. The results obtained were summarized as follows ; 1. The total body weights were decreased in proportion to increment of mercury concentration. The internal organs weights i. e. , liver, kidney, spleen, and heart, were generally increased. Especially, the weight increment of kidney was the highest by intaking of mercuric chloride solution. 2. There were no significant changes in hematocrit values, activities of GOT and GPT in blood of rats receiving mercuric chloride. On the other hand, the plasma levels of cholesterol were significantly increased. The receiving of 200 ppm mercuric chloride solution to rats was resulted in the remarkable reduction of total protein levels and A/G ratio in plasma. 3. The markable rise occured in the accumulation of Hg, in both liver and kidney in proportion to supplying in rats while there was a tendency decreasing of Cu, Zn contents in liver, whereas there was a tendency increasing of Cu, Zn in kidney of rats.
최근(最近) 산업(産業)의 발전(發展)과 더불어 매연(煤煙)이나 발수(廢水)에서 배출(排出)되어 나오는 유기금속화합물유(有機金屬化合物類)는 더욱 더 증가(增加)하여, 직접, 간접으로 우려의 환경(環境)을 오염(汚染)시켜, 인명(人命), 가축(家畜), 식물(植物) 및 수자원(水資源)에까지 심각한 피해(被害)를 끼치고 있다. 그리하여 본실험(本實驗)에서는 금속화합물중(金屬化合物中) 특(特)히 수은(水銀)의 급여(給與)에 의한 급만성중독시(急慢性中毒時) 나타나는 체내(體內) 물질대사(物質代謝)의 영향(影響)에 관한 검사(檢討)를 목적(目的)으로 증류수에
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