Studies on the Efficacy of Combined Preparation of Crude Drugs(XVII) -Effects of ‘Bojungikgi-Tang’ on the Digestive System, Blood Pressure and Diuretic Actions-

생약(生藥) 복합(複合) 제제(製劑)의 약효(藥效) 연구(硏究)(제17보)(第17報) -보중익기탕(補中益氣湯)이 소화기계(消化器系), 혈압(血壓) 및 호흡(呼吸)에 대한 작용(作用)과 이뇨작용(利尿作用)에 미치는 영향(影響)-

Attempts were to investigate the effects of 'Bojungikgi-tang' on the digestive system, blood pressure and diuresis. The results showed that relaxing action was shown on the isolated ileum in mice and that strong antagonistic actions were seen on $BaCl_2$, acetylcholine and histamine-induced contraction of the ileum in mice and guinea-pigs that the relaxing effect of the intestinal smooth muscle was recognized. Inhibitory effects on transport rate in the small intestine of mice and castor oil-induced catharsis in mice were noted. Inhibitory action on the secretion of gastric juice, pH ascending effect and decreasing effect of the free acidity and total acidity were recognized. Continuous hypotensive action was seen, but when the vagus nerve was cut, hypotensive action was remarkably decreased. The diuretic effect was also recognized.