YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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High Performance Liquid Chromatographic Determination of Xanthinol Nicotinate

HPLC에 의한 Xanthinol Nicotinate의 정량(定量)

  • Han, Cho-Duk (College of Pharmacy, Ewha Womans University)
  • 한초덕 (이화여자대학교 약학대학)
  • Published : 1984.12.30
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Abstract

A HPLC determination method of xanthinol nicotinate(I) was developed for study of its stability and characteristics in solutions. I was determined using an ${\mu}-Bondapak\;C_{18}$ column with a mobile phase of methanol: $H_2O$ (1 : 1) and UV absorbance detection at 254nm. The results revealed that the method was enough to use as stability indicating determination with the mean of 99.9% and standard deviation of ${\pm}1.42%$ when analyzed 10 times for standard solution.

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