The Journal of Korean Academy of Prosthodontics (대한치과보철학회지)

The Korean Academy of Prosthodonitics (대한치과보철학회)
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AN EXPERIMENTAL STUDY OF THE CYTOTOXICITY OF SILVERPALLADIUM ALLOYS UPON GINGIVAL FIBROBLAST BY MEANS OF TISSUE CULTURE

치은 섬유아세포(纖維芽細胞)에 대(對)한 은(銀)-파라디움합금(合金)의 세포독성(細胞毒性)에 관(關)한 연구(硏究)

  • Yoon, In-Tak (Dept. of Prosthodontics, Division of Dentistry, Kyung Hee University) ;
  • Choi, Boo-Byung (Dept. of Prosthodontics, Division of Dentistry, Kyung Hee University) ;
  • Kim, In-Chul (Dept. of Prosthodontics, Division of Dentistry, Kyung Hee University)
  • 유인탁 (경희대학교 치과대학 보철학교실) ;
  • 최부병 (경희대학교 치과대학 보철학교실) ;
  • 김인철 (경희대학교 치과대학 보철학교실)
  • Published : 1983.01.01
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Abstract

In order to investigate the biocompatibility of silver-palladium alloys, gingival fibroblast was obtained from a healthy human gingival and cultured in MEM medium with the addition of silverpalladium alloys. Four different mixture of silver-palladium alloys comprising of Ag-Pd-Au, Ag-Pd-In and Ag-Sn were tested. Results were assessed by calculating the cell multiplication rate per millimeter of medium and morphological changes in cells were also observed and noted.The obtained results were as follows; 1. Ag-Pd-Au alloy was indicated to be most biocompatible with gingival fibroblast. Also there was a decrease in cytotoxicity of the alloy as the concentration of gold increased. 2. Ag-Pd alloy showed a decrease in cell multiplication rate as compared to Ag-Pd~Au alloy. 3. Silver-palladium alloy supplemented with Indium increased the cell multiplication rate. 4. Among the alloys tested, Ag-Sn alloy was indicated to be the most cytotoxic and the least biocompatible with human gingival fibroblast.

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