Radiation Oncology Journal
- 제1권1호
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- Pages.85-94
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- 1983
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
비인강암(鼻咽腔癌) 방사선치료성적(放射線治療成績)
The Radiotherapy Result of the Nasopharyngeal Carcinoma
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박찬일
(서울대학교 의과대학 방사선과학교실) ;
- 고경환 (서울대학교 의과대학 방사선과학교실) ;
- 김종선 (서울대학교 의과대학 이비인후과학교실) ;
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김노경
(서울대학교 의과대학 내과학교실)
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Park, Charn Il
(Department of Radiology, College of Medicine, Seoul National University) ;
- Koh, Kyoung Hwan (Department of Radiology, College of Medicine, Seoul National University) ;
- Kim, Chong Sun ;
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Kim, Noe Kyeong
- 발행 : 1983.10.30
초록
A total of 47 patients with a diagnosis of nasopharyngeal carcinoma was treated in Department of Therapeutic Radiology, Seoul National University Hospital during last 4 years. Of the 47 patients, 23(49%) had undifferentiated carcinoma, 20(43%) had squamous cell carcinoma, while 4(8%) had lymphoepithelioma. Most of the patients(71%) has Stage IV disease, cervical lymph node metastases were found in 36(77%) and distant metastasis was found in 1 at the time of diagnosis. Complete response rate after radiotherapy for 47 patients of nasopharyngeal carcinoma was 85.1%. The overall actuarial 3 year survival rates was 0.718 and the disease free actuarial 3 year survival rates was 0.468. Nodal involvement and symptom duration were statistically significiant influencing factors for actuarial survival rate. Treatment failures were found in 20 patients (42.6%), local recurrence only in 6(30%), local and neck recurrence in 3(15%), local recurrence with metastasis in 4(20%) and distant metastasis only in 7(35%). Local failures were more frequent in the patients with cranial nerve symptoms (P=0.032). Distant metastases were more frequent with T4 lesions (P=0.047), and with nodal involvement (P<0.01). Retreatment after the tumor recurrence was chemotherapy and/or radiotherapy, two pationts refreated for local recurrence were alive without evidence of disease for more than 19 and 44 months after retreatment.
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