The Korean Journal of Nuclear Medicine (대한핵의학회지)
- Volume 17 Issue 2
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- Pages.71-77
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- 1983
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- 1225-6714(pISSN)
Preparation of Radiopharmaceuticals through Arylthallium Ditrifluoroacetate Intermediate
Arylthallium ditrifluoroacetate를 중간체(中間體)로 하는 방사성의약품(放射性醫藥品)의 합성법(合成法)
Abstract
Amino acids such as L-tyrosine, L-histidine, and tryptophan, which bear an aromatic ring in the molecule, could successfully be labelled by radioactive iodine through arylthallium ditrifluoroacetate intermediate. Generally, the labelling reaction could proceed in a short labelling time(ca, 20 minutes) and resulted in a high labelling yields and purity of the labelled product. This procedure has, therefore, been proved to be effective as the labelling method of short labelling time and high specific activity. Labelling proteins such as oval albumin and human albumin could also be achieved in
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