Bulletin of the Korean Chemical Society

  • 제4권4호
  • /
  • Pages.183-188
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  • 1983
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  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Polyacetylene Compounds from Panax Ginseng C. A. Meyer

  • Shim, Sang-Chul (The Korea Advanced Institute of Science and Technology) ;
  • Koh, Hun-Yeoung (The Korea Advanced Institute of Science and Technology) ;
  • Han, Byung-Hoon (Natrural Products Research Institute, Seoul National University)
  • 발행 : 1983.08.20
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초록

Two major and two minor polyacetylenes were isolated from fresh white Korean ginseng roots. The petroleum ether-ethyl ether fractions containing the polyacetylene compounds were collected through solvent fractionation, partition and silica gel column chromatography. Further separation of polyacetylenic fractions was proceeded by bonded normal phase HPLC utilizing a moderately nonpolar microparticulate column. The low pressure liquid chromatography was used for the semi-preparative separation. The chemical structures of the two major polyacetylenes separated were determined by UV, IR, $^1H$ NMR, $^{13}C$ NMR, mass spectra and elemental analysis. One of them is identified to be heptadeca-1-en-4, 6-diyne-3, 9, 10-triol, a new structure, and the other is heptadeca-1, 9-dien-4, 6-diyn-3-ol, known as panaxynol.

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참고문헌

  1. Korean Ginseng J.-H. Kim;H.-W. Bae(ed.)
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피인용 문헌

  1. Bioactive polyacetylenes in food plants of the Apiaceae family: Occurrence, bioactivity and analysis vol.41, pp.3, 1983, https://doi.org/10.1016/j.jpba.2006.01.057
  2. Bioactive C 17 and C 18 Acetylenic Oxylipins from Terrestrial Plants as Potential Lead Compounds for Anticancer Drug Development vol.25, pp.11, 1983, https://doi.org/10.3390/molecules25112568
  3. Physiological and pharmacological features of the non-saponin components in Korean Red Ginseng vol.44, pp.4, 1983, https://doi.org/10.1016/j.jgr.2020.01.005