Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Syntheses of Phosphonamides Containing Aminobenzylphosphonic Acid and Aminopenicillanic Acid

  • Hong, Suk-In (Department of Chemical Enginneering, College of Engineering, Korea University) ;
  • Kim, Chang-Sick (Department of Chemical Enginneering, College of Engineering, Korea University) ;
  • Kim, Yong-Joon (Department of Chemical Enginneering, College of Engineering, Korea University)
  • Published : 1983.08.20
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Abstract

This paper reports new phosphonamide derivatives which contain diethyl aminomethylphosphonate, diethyl DL-1-aminobenzylphosphonate and 6-aminopenicillanic acid; N-(ethyl phthalimidomethylphosphonyl)-L-methionine methyl ester, N-(ethyl phthalimidomethylphosphonyl)-L-valine ethyl ester, N-[ethyl N-(methoxycarbonylmethyl)benzylphosphonamido]-2-phthalimidoacetamide, N-[ethyl N-(diethyl phosphonylbenzyl)methylphthalamido] phthalimide, N-[ethyl {ethyl N-(diethyl phosphonylbenzyl)aminomethylphosphonamido} phosphonylmethyl] phthalimide, N-[ethyl N-(diethyl phosphonylbenzyl)methylphosphonamido]-2-phthalimidoacetamide, N, N'-bis (ethyl phthalimidomethylphosphonyl)ethylene diamine, 6-(ethyl DL-1-aminobenzylphosphonamido) penicillanic acid, ethyl N-(ethoxycarbonylmethyl)-1-aminobenzylphosphonamide, ethyl N-(diethyl phosphonylbenzyl)aminomethylphosphonamide and N,N'-bis (ethyl aminomethylphosphonyl) ethylene diamine.

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  1. Phosphonodipeptides containing (2-aminoethyl)phosphonic acid (ciliatine): transition state analogue inhibitors of carboxypeptidase A vol.827, pp.3, 1983, https://doi.org/10.1016/0167-4838(85)90212-2