Anti-inflammatory and Analgesic Activities of the Root of Caragana koreana

"참골담초"근(根)의 소염(消炎) 및 진통작용(鎭痛作用)에 관(關)한 연구(硏究)

The studies on the anti-inflammatory and analgesic activities were carried out to develop the domestic natural sources of the underground parts of Caragana koreana Nakai (Leguminosae), which have been used for the treatment of neuralgia, arthritis, and gout etc. in folk remedies. The methanol extract of the root was shown significant antiinflammatory effect in the paw edema induced by carrageenin, and also indicated remarkable preventive and therapeutic effects to chronic arthritis model induced by Freund's complete adjuvant in rats. It also has inhibited significantly the increase in vascular permeability and the number of writhings induced by acetic acid in mice.