The Journal of the Korean Society for Microbiology (대한미생물학회지)
- Volume 17 Issue 1
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- Pages.7-14
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- 1982
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- 0253-3162(pISSN)
A Role of Natural Killer Cell in Mouse Infected Herpes Simplex Virus
Herpes Simplex Virus에 감염된 Mouse의 NK세포역할
- Lee, Yun-Tai (Department of Microbiology, Catholic Medical College) ;
- Lee, Chong-Hoon (Department of Microbiology, Catholic Medical College)
- Published : 1982.12.31
Abstract
A model of induction of neoplasia by viruses has develpoed from experimental studies in animals and in cultured cells and oncogenic transformation of cells is the result of integration of viral genetic information into the cellular DNA. The evidence for these associations was derived primarily from seroepidemiologic investigation. However, data indicating that the relation between HSV-2 and cervical cancer fits the model derived from experimental animal studies are not yet sufficient to draw conclusion with regard to the etiologic role the virus in the development of the neoplasms. In other hand, the K562 tumor cell is highly susceptible target for natural killer cell lysis by the lymphocytes of human and murine periperal blood. The characteristics of this effector cell type has been investigated. A study on natural killer cell mediated cytotoxicity(NKMC) against
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