Electron Microscopic Observations on BHK-21 Cells Infected with Herpes Simplex Type 2 Virus

Herpes Simplex 2형 바이러스의 BHK-21 세포내에서의 전자현미경적 관찰

  • Ko, Kwang-Kjune (Department of Microbiology, Catholic Medical College) ;
  • Lee, Yun-Tai (Department of Microbiology, Catholic Medical College) ;
  • Lee, Chong-Hoon (Department of Microbiology, Catholic Medical College)
  • 고광균 (가톨릭대학 의학부 미생물학교실) ;
  • 이연태 (가톨릭대학 의학부 미생물학교실) ;
  • 이종훈 (가톨릭대학 의학부 미생물학교실)
  • Published : 1981.12.31

Abstract

An electron microscopic study was carried out on the morphogenesis of herpes simplex type 2 virus in BHK-21 cells BHK-21 cells was found susceptible to infection and replication of herpes simplex type 2 virus cytopathic effects of the herpes type appeared at approximately 1 day postinoculation. Foci consisting of rounded refractile cells and syncytia were observed. Projection of the nuclear membrane in the infected cells was also seen, Several infected cells showed a track-shaped structure which apparently consisted of multiple layered membranes of the nucleus.

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