The Korean Journal of Nuclear Medicine (대한핵의학회지)
- Volume 15 Issue 1
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- Pages.37-43
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- 1981
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- 1225-6714(pISSN)
A Case of Congenital Hypothyroidism Due to Organification Defect Associated with Huerthle Cell Adenoma
세포선종(細胞線腫)이 병발(竝發)된 1예(例)">
Organification장애(障碍)에 의한 선천성(先天性) 갑상선기능저하증(甲狀線機能低下症)과 $H\"{u}rthle$ 세포선종(細胞線腫)이 병발(竝發)된 1예(例)
- Kim, Byung-Tae (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Lee, Kee-Sang (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Chung, Soon-Il (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Kim, Sam-Yong (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Cho, Kyung-Sam (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Cho, Bo-Yeon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University)
- 김병태 (서울대학교병원 내과) ;
- 이기상 (서울대학교병원 내과) ;
- 정순일 (서울대학교병원 내과) ;
- 김삼용 (서울대학교병원 내과) ;
- 조경빈 (서울대학교병원 내과) ;
- 조보연 (서울대학교병원 내과) ;
- 고창순 (서울대학교병원 내과)
- Published : 1981.06.30
Abstract
Congenital hypothyroidism due to organification defect was first reported by Haddad and Sidbury in 1959. The organification defect is easily proved by perchlorate discharge test. We experienced a patient who had large goiter, growth and mental retardation, and revealed positive reponse to perchlorate discharges test, and the surgical biopsied specimen showed Huerthle cell adenoma, which was probably due to chronic stimulation of thyroid stimulating hormone, or coexisted incidentally. Described here a case of congenital hypothyroidism due to organification defect associated with Huerthle cell adenoma, with review of some literatures.
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