Korean Journal of Pharmacognosy (생약학회지)
- Volume 12 Issue 1
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- Pages.55-57
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- 1981
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Antihypertensive Activity of Korean Medicinal Plants Against Okamoto-SHR (I)
오카모토 고혈압쥐에 대한 한국산생약의 항고혈압작용 (I)
- Chang, Il-Moo (Natural Products Research Institute, Seoul National University) ;
- Park, Young-Choon (Natural Products Research Institute, Seoul National University) ;
- Kim, Jae-Hoon (Natural Products Research Institute, Seoul National University) ;
- Han, Koo-Dong (Natural Products Research Institute, Seoul National University) ;
- Lee, Jong-Heun (College of Dentistry, Seoul National University) ;
- Kim, Joong-Soo (College of Dentistry, Seoul National University)
- 장일무 (서울대학교 생약연구소) ;
- 박영춘 (서울대학교 생약연구소) ;
- 김제훈 (서울대학교 생약연구소) ;
- 한구동 (서울대학교 생약연구소) ;
- 이종흔 (서울대학교 치과대학) ;
- 김중수 (서울대학교 치과대학)
- Published : 1981.03.30
Abstract
Six medicinal plants described in Dong-Ee-Bo-Gam as to be useful for hypertension treatment were evaluated their antihypertensive activity against Okamoto-SHR, an animal model of spontaneous hypertension. Ethanol extracts of plant samples were prepared and were p.o. administered once daily for 20 days. Average blood pressures of rats were measured during two weeks periods before drug administration. Then blood pressure of each rat was measured every three days during drug administration period. As a positive control, propranolol,
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