Studies on Histological Changes of Bursa of Fabricius in Chicken Treated with Thyroxine; I. Light Microscopic Observations on Bursa of Fabricius Including Other Organs in Chicken Administrated with Thyroxine or PropylthiouraciI

갑상선(甲狀腺) 호르몬이 닭의 Fabricius 낭(囊)에 미치는 조직학적변화(組織學的變化)에 관(關)한 연구(硏究) I. Thyroxine 및 Propylthiouracil을 투여(投與)한 닭의 Fabricius낭(囊) 및 기타(其他) 장기(臟器) 대(對)한 광학현미경적관찰(光學顯微鏡的觀察)

In order to know the effects of thyroid hormone on the bursa of Fabricius in chicken, the bursae were studied with the light microscope after administration of thyroxine(TX) or propylthiouracil(PPT). Macroscopically, the bursa of TY-treated group showed increase in size and thickened folds. while those of the PPT-treated group decrease in size, compared with those of control group. In the light microscopic studies, the bursa of Fabricius of the TX-treated group showed active cell-divisions in the medulla, and increased number of pyroninophilic large lymphocytes and plasma cells containing PAS positive materials in the cytoplasms. On the other hand, the bursa from PPT-treated group revealed decreased number of lymphocytes, significant increase of necrotic lymphocytes in the follicles, and the proliferation of the interfollicular connective tissues. A large number of pyroninophilic lymphocytes and plasma cells were also appeared in the spleen of the TX-treated group.