The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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A Study on the Serum Myoglobin Levels in Thyroid Diseases

각종 갑상선질환(甲狀腺疾患)에서의 혈청(血淸) myoglobin 치(値)에 관(關)한 연구(硏究)

  • Cho, Bo-Yeon (Dept. of Int. med., College of Medicine, Seoul National University) ;
  • Chang, Youn-Bok (Dept. of Int. med., College of Medicine, Seoul National University) ;
  • Cho, Kyong-Sam (Dept. of Int. med., College of Medicine, Seoul National University) ;
  • Chung, Soon-Il (Dept. of Int. med., College of Medicine, Seoul National University) ;
  • Kim, Sam-Yong (Dept. of Int. med., College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Dept. of Int. med., College of Medicine, Seoul National University) ;
  • Lee, Mun-Ho (Dept. of Int. med., College of Medicine, Seoul National University)
  • 조보연 (서울대학교 의과대학 내과학교실) ;
  • 장연복 (서울대학교 의과대학 내과학교실) ;
  • 조경삼 (서울대학교 의과대학 내과학교실) ;
  • 정순일 (서울대학교 의과대학 내과학교실) ;
  • 김삼용 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 이문호 (서울대학교 의과대학 내과학교실)
  • Published : 1980.12.30
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Abstract

To evaluate the change of serum myoglobin in the thyroid disease, we measured serum myoglobin by radioimmunoassay in 24 normal subjects, 34 patients with hyperthyroidism (20 untreated, 14 treated) and 5 patients with hypothyroidism. The mean values of serum myoglobin in 24 normal control, 20 untreated hyperthyroidism, and 14 treated hyperthyroidism were $50.9{\pm}17.0ng/ml,\;39.1{\pm}20.3ng/ml\;and\;51.0{\pm}18.3ng/ml$ respectively. The serum myoglobin level of untreated hyperthyroidism seemed to be lower than that of normal control without statistical significance. The serum myoglobin levels in 5 patients with hypothyroidism ranged 28-156 ng/ml, and 3 patients showed increased serum myoglobin level. We observed one case with severe degree of thyrotoxic myopathy whose serum myoglobin level was markedly elevated initially and was decreased to normal range after treatment. This results suggests that the determination of serum myoglobin might be useful in the evaluation of thyrotoxic myopathy.

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