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Synthesis of Pentapeptide Containing DL-1-Aminobenzylphosphonic Acid

  • Hong, Suk-In (Department of Chemical Engineering, College of Engineering, Korea University) ;
  • Kim, Yong-Joon (Department of Chemical Engineering, College of Engineering, Korea University)
  • Published : 1980.09.30

Abstract

Six previously unreported peptides containing diethyl DL-1-aminobenzylphosphonate terminal unit were prepared. These are: Diethyl phthalyl-glycyl-gly-DL-1-aminobenzylphosphonate, diethyl gly-gly-DL-aminobenzylphosphonate, diethyl phthalyl-gly-gly-gly-DL-1-aminobenzylphosphonate , diethyl phthalyl-gly-gly-gly-gly-DL-1-aminobenzylphosphonate, diethyl phthalyl-DL-1-phenylalanyl-DL-1-aminobenzylphosphonate, diethyl phthalyl-gly-DL-phenylalanyl-DL-1-aminobenzylphosphonate. All the compounds were obtained as white crystalline powder and characterized by means of elemental analysis, IR spectroscopy, NMR spectroscopy, and ninhydrin test.

Keywords

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