Korean Journal of Pharmacognosy (생약학회지)
- Volume 11 Issue 1
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- Pages.11-14
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- 1980
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
A Study of the Effects of the Root Components of Angelica gigas Nakai on Voluntary Activity in Mice
참당귀 성분(成分)이 생쥐 자발운동(自發運動)에 미치는 영향(影響)
- Kim, Hack-Seang (College of Pharmacy, Chung Buk National University) ;
- Park, Jung-Sup (College of Pharmacy, Chung Buk National University) ;
- Park, Hae-Ja (College of Pharmacy, Chung Buk National University) ;
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Chi, Hyung-Joon
(Natural Products Research Institute, Seoul National University)
- Published : 1980.03.30
Abstract
A Study of the effects of the root components of Angelica gigas Nakai (Umbelliferae) on voluntary activity in mice has confirmed that there are: 1) MeOH soluble extract, MeOH insoluble extract, decursin and decursinol were antagonized against the voluntary activity in mice pretreated with a dose of caffeine natrium benzoate 30mg/kg. 2) MeOH insoluble extract showed higher depressant effect than MeOH soluble extract. 3) The depressant activity of decursinol was significantly more highly effective than that of decursin.
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