대한화학회지 (Journal of the Korean Chemical Society)

  • 제23권2호
  • /
  • Pages.94-98
  • /
  • 1979
  • /
  • 1017-2548(pISSN)
  • /
  • 2234-8530(eISSN)
대한화학회 (Korean Chemical Society)
권호 표지

2-Amino-와 2-Nitro-3,4-dihydro-5,6-dimethoxy-1(2H)-naphthalenone의 촉매수소화에서 5,6-Dimethoxy-1,2,3,4-tetrahydro-2(1H)-naphthalenone의 분리 및 구조결정

Isolation and Characterization of 5,6-Dimethoxy-1,2,3,4-tetrahydro-2(1H)-naphthalenone from Catalytic Reductions of the Respective 2-Amino-, and 2-Nitro-3,4-dihydro-5,6-dimethoxy-1(2H)-naphthalenone

  • 김정균 (부산대학교 문리과대학 화학과)
  • Kim Jack C. (Department of Chemistry, Busan National University)
  • 발행 : 1979.04.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

2-Amino-와 2-nitro-3,4-dihydro-5,6-dimethoxy-1(2H)-naphthalenone의 촉매수소화에서 주생성물인 2-amino-5,6-dimethoxy-1,2,3,4-tetrahydronaphthalene을 얻었고 동시에 극소량의 5,6-dimethoxy-1,2,3,4-tetrahydro-2(1H)-naphthalenone을 얻었다. 이 전이된 생성물의 구조결정은 ir와 nmr, 그리고 원소분석으로 확인하였고 전이메카니즘을 제시하였다.

From the catalytic reductions of the respective 2-amino-, and 2-nitro-3,4-dihydro-5,6-dimethoxy-1(2H)-naphthalenone, a major reduction product of 2-amino-5,6-dimethoxy-1,2,3,4-tetrahydro-naphthalene was obtained, along with a minute amount of rearranged product, 5,6-dimethoxy-1,2,3,4-tetrahydro-2(1H)-naphthalenone. The unusual formation of 5,6-dimethoxy-1,2,3,4-tetrahydro-2(1H)-naphthalenone was verified on the basis of ir, and nmr spectra, and elemental analysis. A plausible mechanism for the rearrangement is proposed.

키워드

참고문헌

  1. J. Kor. Chem. Soc. v.20 J. C. Kim;S. K. Han;S. K. Choi
  2. J. Kor. Chem. Soc. v.21 J. C. Kim
  3. J. Med. Chem. v.15 J. G. Cannon;J. C. Kim
  4. ASPET MEETING, Abstract 129. J. C. Kim;J. G. Cannon;J. P. Long and S. Heintz
  5. J. Pharmacol. Exp. Ther. v.192 J. P. Long;S. Heintz;J. G. Cannon;J. C. Kim
  6. U. S. Patent 374,170 J. G. Cannon;J. C. Kim
  7. J. Heterocycl. Chem. v.9 J. G. Cannon;J. C. Kim;A. M. Aleem
  8. J. Med. Chem. v.12 W. K. Sprenger(et al.)
  9. J. Med. Chem. v.17 J. G. Cannon;J. P. O'Donnell;J. P. Rosazza;C. R. Hoppin
  10. Tetrahdron v.24 R. L. Hinman
  11. Tetrahedron Letters no.17 J. Ficini;A. Krief
  12. J. Amer. Chem. Soc. v.92 P. Y. Sollenberger;R. B. Martin