Archives of Pharmacal Research
- 제2권2호
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- Pages.153-157
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- 1979
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Studies on the Constituents of Higher Fungi of Korea (XXIV)
- Park, Eun-Kyue (Department of Microbial Chemistry, College of Pharmacy, Seoul National University) ;
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Choi, Eung-Chil
(Department of Microbial Chemistry, College of Pharmacy, Seoul National University) ;
- Kim, Byong-Kak (Department of Microbial Chemistry, College of Pharmacy, Seoul National University)
- 발행 : 1979.12.01
초록
The carpophores of three Korean mushrooms, Coriolus versicolor, Pleurotus ostreatus, and Lentinus edodes were respectively extracted with hot water and the extract were dialyzed through Visking tube. They were found to contain an antinumor activity against sarcoma 180 implanted in mice. The components of these aqueous extracts were found to be polysaccharide and protein by color reactions including anthrone and Lowry-Folin tests. The hydrolysis of the polysaccharide with 3% HCI-MeOH and trimethylsilylation yielded four monosaccharides : glucose, mannose, galactose and xylose which were identified by G. L. C. After hydrolysis of protein with 6N HCL, fourteen to seventeen amino acids including aspartic and glutamic acids were detected by an amino acid analyzer.
키워드
- Basidiomycetes-the family Poly-porceae-Coriolus versicolor;
- Plevrotus ostreatrs;
- and Lentinus edodes;
- Chemical analyses of the antineoplastic components-identification of four monosaccharides: glocose;
- mannose;
- galactose and xylose of the antitumor polysaccharides;
- Identification of 14~17 amino acids of the protein fractions of the antitumor extracts.;