The Journal of the Korean Society for Microbiology (대한미생물학회지)
- Volume 13 Issue 1
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- Pages.49-54
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- 1978
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- 0253-3162(pISSN)
Antibody to Propionibacterium acnes in Normal Human and Hepatoma Patients
정상인(正常人) 및 간암환자(肝癌患者)의 Propionibacterium acnes에 대(對)한 항체(抗體)
- Ha, Tai-You (Department of Microbiology, Jeonbug University Medical School)
- 하대유 (전북대학교 의과대학 미생물학교실)
- Published : 1978.12.31
Abstract
Antibodies to Propionibacterium acnes in patients with tumor, leprosy, schizophrenia and normal human were measured by using a microtiter bacterial agglutination test. They were found in all sera examined, including normal human sera. It was comfirmed that a microtiter bacterial agglutination test on P. acnes is found to be an easy and satisfactory method for the measurement of antibody to P. acnes. The agglutinin titers of tumor patients, particularly hepatoma and gastric cancer patients, were significantly lower as compared with those of normal human sera. Antibody titers in leprosy patients were somewhat lower when compared with those in normal human sera. Antibody titers of lepromatous type of leprosy patient were lower than those of tuberculoid type. However, antibody levels were the same in schizophrenia patient and normal human. No correlation between antibody titers and age or sex of the patients and normal human was found.
응집반응(凝集反應)을 이용(利用)하여 각종(各種) 종양환자(腫瘍患者), 정신분열증환자(精神分裂症患者) 및 정상인(正常人)의 Propionibacterium acres(동의어(同義語) Corynebacterium parvum))에 대(對)한 항체가(抗體價)를 측정(測定)하였든바 각종환자(各種患者) 및 정상인(正常人)에게 P. acnes에 대(對)한 항체(抗體)가 검색(檢索)되었다. 종양환자(腫瘍患者)의 항체가(抗體價)는 정상인에 비(比)해 유의(有意)하게 저하(低下)되어 있었다. 나환자(癩患者)의 항체가(抗體價)는 다소(多少) 낮았으며, 나종형환자(癩腫型患者)의 항체가(抗體價)는 유결핵형환자(類結核型患者)에 비(比)해 다소(多少) 낮은 경향(傾向)이었다. 그러나 정신분류증환자(精神分類症患者)의 항체가(抗體價)는 정상인(正常人)의 그것과 비슷하였다. 대체적(大體的)으로 각종환자(各種患者) 및 정상인(正常人)에게 연령(年齡) 및 성별(性別)에 따른 항체(抗體) 가(價)로 차이(差異)가 없었다.
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