STUDIES ON THE CLINICAL EFFICACY OF VALIUM AND PENTOBARBITAL AS PREMEDICATING AGENT

준비투약(準備投藥)으로서 Valium, Pentobarbital의 임상적(臨床的) 효과(效果)에 관(關)한 연구(硏究)

To evaluate clinically effect of Valium and Sodium pentobarbital as premedicating agent, both drugs and a placebo were compared in 45 patients (2 to 11 yrs). The results were as follows. 1. Both Sodium pentobarbital and Valium were superior to placebo for control of crying, cooperation and apprehension, but the statistically differences were not significant. 2. Both Valium and Sodium pentobarbital were superior to placebo for control of behavior in tense cooperative child; the differences were significant statistically. 3. The difference between Pentobarbital and Valium were-more pronounced at the initial level than at the subsequent readings, and Sodium pentobarbital was for superior at the initial level to the other drugs. 4. Paradoxical excitement occured in 2 cases on the Sodium pentobarbital group, and other apparent side effect did not occur, excluding mild drowsiness. 5. Neither Valium nor Sodium pentobarbital, as used in this study, resulted in consistantly better behavior in all patients.