The Korean Journal of Pharmacology (대한약리학회지)
- Volume 13 Issue 2
- /
- Pages.67-73
- /
- 1977
- /
- 0377-9459(pISSN)
Nitrogen Sparing Effect of Intravenous Amino Acid Solutions
종합 아미노산수액 투여에 의한 Nitrogen balance의 임상적 검토
- Park, C.W. (Department of Pharmacology, College of Medicine, Seoul National University) ;
- Lim, J.K. (Department of Pharmacology, College of Medicine, Seoul National University) ;
- Lee, J.K. (Cancer Hospital, Korea Atomic Energy Research Institute) ;
- Lee, J.O. (Cancer Hospital, Korea Atomic Energy Research Institute) ;
- Park, K.W. (Cancer Hospital, Korea Atomic Energy Research Institute)
- Published : 1977.12.30
Abstract
The nitrogen sparing effect of intravenous 3% amino acid solution was compared with 5% dextrose solution in 30 patients who were undergoing surgical operations or radiation therapy. Infusion of 3% amino acid solution or 5% dextrose solution was given before and immediately after operations or irradiation and continued for 6 days. Infusion of solutions through peripheral vein was well tolerated and not experienced any specific hematologic or blood chemistry change in all patients subjected throughout the experiment. The patients received 3% amino acid solution showed low blood glucose and insulin level, but significantly high blood urea nitrogen and ketone body. In patients receiving amino acids, as compared with those receiving dextrose, mean cumulative six day nitrogen losses were significantly lower(
Keywords