The Korean Journal of Physiology
- 제10권2호
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- Pages.39-45
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- 1976
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- 0300-4015(pISSN)
흰쥐의 위궤양 발생에 미치는 뇌해마 제거 및 부신 적출의 영향
Influence of Hippocampectomy and Adrenalectomy upon Gastric Ulceration in Rats
- Kim, Myung-Suk (Department of Physiology, Catholic Medical College) ;
- Ahn, Byung-Tae (Department of Physiology, Catholic Medical College) ;
- Kim, Chul (Department of Physiology, Catholic Medical College)
- 발행 : 1976.12.30
초록
This study was conducted to see whether the hippocampectomy exerted facilitatory influence upon gastric ulceration in animals, and if so, whether the effect of hippocampectomy could be suppressed by adrenalectomy. 107 male rats were divided into 5 groups: rats that had over 90% of their hippocampal tissue removed through an opening on each side of the cerebral cortex(hippocampal group, N=21), rats that received bilateral adrenalectomy(adrenal group, N=29), rats that received adrenalectomy as well as hippocampectomy(hippocampo-adrenal group, N=10), rats that received damage to each side of the cortex over the hippocampus(cortical control group, N=20), and rats that had solely their head skin incised(normal control group, N=27). All rats were kept without restraint or food deprivation until on the 25th day after surgery, the stomach of each rat was inflated with 7ml of physiological saline and then removed under deep anesthesia. The mucosal surface was sketched under dissecting microscope, and enlarged photographs
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