대한핵의학회지 (The Korean Journal of Nuclear Medicine)
- 제9권2호
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- Pages.39-46
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- 1975
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- 1225-6714(pISSN)
Erythropoietin 검사법(檢査法)에 관(關)한 연구(硏究)
Studies on Erythropoietin Bioassay Method
- Cho, Kyoung-Sam (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Ro, Heung-Kyu (Department of Internal Medicine, College of Medicine, Seoul National University) ;
- Lee, Mun-Ho (Department of Internal Medicine, College of Medicine, Seoul National University)
- 발행 : 1975.12.05
초록
It is the purpose of this paper to design the most preferable method of erythropoietin bioassay in Korea. Bioassay utilizing polycythemic mice are currently in general use for the indirect determination of erythropoietin. Assay animals are usually prepared either by transfusion or by exposure to reduced oxygen tension in specially constructed chamber. We prepared the polycythemic, mice by the specially constructed hypobaric chamber. We observed weights and hematocrits of the mice in the hypobaric chamber, then hematocrits and 72 hours
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