Studies on the Development of Antihypertensive Agents from Korean Crude Drugs(III) -Influence of Eucommial Cortex of Korea on the Blood Pressure Responses of Rabbits-

혈압강하제 국산 자원생약의 개발에 관한 연구(III) -한국산 두중(杜仲)의 가토(家兎) 혈압(血壓)에 미치는 영향-

Influence of Eucommiae Cortex in Korea on the blood pressure of the rabbit was examined, 1) The intravenous injection of 3 mg/kg, 10 mg/kg and 30 mg/kg of the water extract to the rabbit decreased its blood pressure to $9.7\;{\pm}\;1.9,\;26.4\;{\pm}\;1.7\;and \;35.5\;{\pm}\;2.7\;mmHg$. respectively. 2) The intravenous injection of 10 mg/kg of the water extract did not show any remarkable influence to the blood pressure caused by the intravenous injection of acetylcholine $10^{-8}\;g/kg\; and \;10^{-7}\;g/kg$. 3) The intravenous injection of the water extract after the intravenous injection atropine 2mg/kg did not show any remarkable change to the blood pressure 4) The intravenous injection of the water extract after the intravenous injection of propranolol 2mg/kg slightly decreased the blood pressure.