Studies on the Colorimetric Determination of Drugs with Phosphomolybdic Acid. I. Colorimetric Determination of Ampicillin with Phosphomolybdic acid

  • Lee, Wang-Kyu (Department of Pharmaceutical Analytical Chemistry, College of Pharmacy) ;
  • Yoo, Byung-Tai (Department of Pharmaceutical Analytical Chemistry, College of Pharmacy) ;
  • Kang, Gil-Jong (Department of Pharmaceutical Analytical Chemistry, College of Pharmacy)
  • Published : 1974.09.01

Abstract

A new colorimetric method established for the determination of ampicillin was based on the reductions of phosphomolybdic acid by ampicillin to be resutled in a molybdenum blue which showed a mezimal absorbance at 770nm. The pH effects on a molybodenum blue solution was dependent significantly on temeprature, but the wave-length shift was not effected by the molybdenum blue.

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