Studies on the Population of Toxigenic Fungi in Foodstuffs - VI. Screening Tests Using HeLa Cells and Mice for Detection of Mycotoxin-Producing Fungi

한국(韓國) 식품중(食品中)의 유독성(有毒性) 진균(眞菌)에 관(關)한 연구(硏究) - VI. HeLa Cell 및 마우스를 이용(利用)한 Mycotoxin 분비균주(分泌菌株) 검색(檢索)

  • Cho, Seh-Hoon (Department of Microbiology, Yonsei University College of Medicine) ;
  • Koh, Choon-Myung (Department of Microbiology, Yonsei University College of Medicine) ;
  • Choi, Tae-Joo (Department of Microbiology, Yonsei University College of Medicine) ;
  • Lew, Joon (Department of Microbiology, Yonsei University College of Medicine)
  • 조세훈 (연세대학교 의과대학 미생물학교실) ;
  • 고춘명 (연세대학교 의과대학 미생물학교실) ;
  • 최태주 (연세대학교 의과대학 미생물학교실) ;
  • 유준 (연세대학교 의과대학 미생물학교실)
  • Published : 1973.12.31

Abstract

Twenty culture filtrates among the various isolated strains from foodstuffs were submitted for toxicity screening using HeLa cells and mice. Fourteen strains(70%) were toxic to both HeLa cells and mice, 17 strains(85%) to HeLa cell alone and 14 strains(70%) to mice alone. As a mass screening this method employed is feasible to detect mycotoxin-producing fungi. In most instances, the results obtained by HeLa cells were in good parellelism with those obtained by mice.

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