$\gamma$,$\gamma$,$\gamma$-Trichloroethylidene-m-Nitroacetophenone과 Hydrazine 들의 반응

Reactions of $\gamma$,$\gamma$,$\gamma$-Trichloroethylidene-m-Nitroacetophenone with Hydrazines

$\gamma$,$\gamma$,$\gamma$-Trichloroethylidene-m-Nitroacetophenone과 phenylhydrazine및 치환된 phenylhydrazine들과의 반응으로 2,6-disubstituted-3-pyridazinone들을 합성하였으며 2,4-dinitrophenylhydrazine과의 반응에서는 hydrazone을 중간체로 분리하였다. hydrazinehydrate와의 반응에서는 3-(mnitrophenyl)-5-trichloromethyl-2-pyrazoline이 좋은 수득률로 얻어졌다. 또한$\gamma$,$\gamma$,$\gamma$-trichloroethylidene-m-nitroacetophenone과 치환된 phenylhydrazine과의 반응에서 phenyl기에 결합된 치환기의 효과를 검토하였다.

2,6-Disubstituted-3-pyridazinones were synthesized by the reactions of $\gamma$,$\gamma$,$\gamma$-trichloroethylidene-m-nitroacetophenone with phenylhydrazine and substituted phenylhydrazines, and hydrazone was isolated as an intermediate from the reaction with 2, 4-dinitrophenylhydrazine. From the reaction with hydrazine hydrate 3-(m-nitrophenyl)-5-trichloromethyl-2-pyrazoline was obtained in good yield. The effect of substituents on phenyl group in the reaction of $\gamma$,$\gamma$,$\gamma$-trichloroethylidene-m-nitroacetophenone with substituted phenylhydrazines was also discussed.